The Center for Diagnostics and Therapeutics is an interdisciplinary initiative to realize viable applications of research discoveries.
The Center for Diagnostics and Therapeutics would like to welcome our newest members, Dr. Ming Luo, Professor of Chemistry and Jessica McFarlane, CDT’s Administrative Coordinator.
Dr. Ming Luo received his Bachelor of Science degree from the Department of Chemistry, Wuhan University, China, in 1982. He did his graduate work on crystal structure of picornaviruses and antiviral drugs in Purdue University, Indiana, and received his Ph.D. degree in Biological Sciences in 1987. Dr. Luo joined the faculty of the University of Alabama at Birmingham as an Assistant Professor in the Department of Microbiology in 1987 and was promoted to Full Professor in 1996. He was Associate Director of Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham. He is trained as a protein crystallographer and has been studying protein structures, especially structure of viruses through his career. He was awarded the Sidhu Award of the Pittsburgh Diffraction Society in 1989. Dr. Luo joined Georgia State University as a Professor in the Department of Chemistry (http://chemistry.gsu.edu/profile/ming-luo/) and a member of the Center for Diagnostics and Therapeutics in 2014.
Emerging viruses continue to be a threat to global health and social stability. The capability of rapid responses depends our knowledge of virus growth and spread, and possible stockpiles of counter measures. Dr. Ming Luo’s group works on novel approaches to unveil virus replication mechanisms by use of structural information. The group of viruses he works on are negative strand RNA viruses, including influenza virus, Ebola virus, mumps virus and vesicular stomatitis virus.
Antiviral drugs are valuable counter measures because their stockpiling is logistically more practical and cost-effective. To create antiviral drugs that are efficacious against all variants of the targeted virus, we use the crystal structure of viral proteins to guide the chemical design of drug structure. The viral proteins that are responsible for the virus release and viral RNA synthesis have been selected as targets of anti-flu drugs. The structure-aided strategy will facilitate our efforts to develop a potent inhibitor that is effective against all influenza virus strains that cause human infections.
Dr. Jenny Yang, CDT Associate Director, has been named a Distinguished University Professor by Georgia State University. Read more »
Center for Diagnostics and Therapeutics
Georgia State University
P.O. Box 5090
Atlanta, GA 30303-5090
Jessica McFarlane is the Administrative Coordinator for The Center for Diagnostics and Therapeutics (CDT). She came all the way from sunny South Florida to be with us, here in Atlanta. She received her Bachelor’s degree in Anthropology & Sociology from Florida International University, in Miami, FL, and her Master’s degree in Human Resource Management from Nova Southeastern University, in Ft. Lauderdale, FL